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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CLCNKA All Species: 28.79
Human Site: Y93 Identified Species: 57.58
UniProt: P51800 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P51800 NP_001036169.1 687 75285 Y93 G D S H L L R Y L S W T V Y P
Chimpanzee Pan troglodytes XP_525229 687 75266 Y93 G D S H L L R Y L S W T V Y P
Rhesus Macaque Macaca mulatta XP_001091784 740 81203 Y93 T Q G H M L R Y L S W T V Y P
Dog Lupus familis XP_544547 687 75469 Y93 G D S H L L R Y L S W T V Y P
Cat Felis silvestris
Mouse Mus musculus Q9WUB7 687 75650 Y93 G D G H L L R Y L S W T V Y P
Rat Rattus norvegicus Q06393 687 75551 Y93 G D G H L L R Y L S W T V Y P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_425749 696 76448 Y91 G D Y L V L K Y L S W T I Y P
Frog Xenopus laevis NP_001079308 689 76782 Y94 G G N V L L R Y L S W I V Y P
Zebra Danio Brachydanio rerio NP_956676 693 75983 F114 K G H H L L Q F L C W T L Y P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VGH7 1193 133629 V213 D L T S Q P F V Q Y I A W V S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P60300 763 83497 F116 A G R F A M G F V V F S V T N
Baker's Yeast Sacchar. cerevisiae P37020 779 87664 E126 C C N G V V N E V T S T S N L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.2 81.3 87.4 N.A. 82.5 83.2 N.A. N.A. 60 61.9 43.5 N.A. 27.4 N.A. N.A. N.A.
Protein Similarity: 100 97.5 86.2 93 N.A. 90.8 91.2 N.A. N.A. 73.5 78.5 62.1 N.A. 39.8 N.A. N.A. N.A.
P-Site Identity: 100 100 73.3 100 N.A. 93.3 93.3 N.A. N.A. 66.6 73.3 53.3 N.A. 0 N.A. N.A. N.A.
P-Site Similarity: 100 100 80 100 N.A. 93.3 93.3 N.A. N.A. 86.6 80 73.3 N.A. 6.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 20.4 24.6 N.A.
Protein Similarity: N.A. N.A. N.A. 39.4 43.3 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 40 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 0 0 9 0 0 0 0 0 0 9 0 0 0 % A
% Cys: 9 9 0 0 0 0 0 0 0 9 0 0 0 0 0 % C
% Asp: 9 50 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 9 0 0 9 17 0 0 9 0 0 0 0 % F
% Gly: 59 25 25 9 0 0 9 0 0 0 0 0 0 0 0 % G
% His: 0 0 9 59 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 9 9 9 0 0 % I
% Lys: 9 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % K
% Leu: 0 9 0 9 59 75 0 0 75 0 0 0 9 0 9 % L
% Met: 0 0 0 0 9 9 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 17 0 0 0 9 0 0 0 0 0 0 9 9 % N
% Pro: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 75 % P
% Gln: 0 9 0 0 9 0 9 0 9 0 0 0 0 0 0 % Q
% Arg: 0 0 9 0 0 0 59 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 25 9 0 0 0 0 0 67 9 9 9 0 9 % S
% Thr: 9 0 9 0 0 0 0 0 0 9 0 75 0 9 0 % T
% Val: 0 0 0 9 17 9 0 9 17 9 0 0 67 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 75 0 9 0 0 % W
% Tyr: 0 0 9 0 0 0 0 67 0 9 0 0 0 75 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _